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1

Nonpeptidal peptidomimetics with .beta.-D-glucose scaffolding. A partial somatostatin agonist bearing a close structural relationship to a potent, selective substance P antagonist

Hirschmann, Ralph, Nicolaou, K. C., Pietranico, Sherrie, Salvino, Joseph, Leahy, Ellen M., Sprengeler, Paul A., Furst, George, Strader, Catherine D., Smith, Amos B.

Journal:

Journal of the American Chemical Society

Year:

1992

Language:

english

File:

PDF, 290 KB

english, 1992

2

Randomized Controlled Trials of the D1/D5 Antagonist Ecopipam for Weight Loss in Obese Subjects

Arne Astrup, Frank L. Greenway, Walter Ling, Lisa Pedicone, Jean Lachowicz, Catherine D. Strader, Rudolf Kwan, Ecopipam Obesity Study Group

Journal:

Year:

2007

Language:

english

File:

PDF, 240 KB

english, 2007

3

L-750355, a human ß3-adrenoceptor agonist; in vitro pharmacology and profile of activity in vivo in the rhesus monkey

Michael J Forrest, Gary Hom, Tom Bach, Mari Rios Candelore, Margaret A Cascieri, Catherine Strader, Laurie Tota, Michael H Fisher, John Szumiloski, Hyun O Ok, Ann E Weber, Matthew Wyvratt, Pasquale Vi

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 169 KB

english, 2000

4

An Updated Review of Iclaprim: A Potent and Rapidly Bactericidal Antibiotic for the Treatment of Skin and Skin Structure Infections and Nosocomial Pneumonia Caused By Gram-Positive Including Multidrug Resistant Bacteria

Huang, David B, Strader, Catherine D, MacDonald, James S, VanArendonk, Mark, Peck, Richard, Holland, Thomas

Journal:

Open Forum Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 1.17 MB

english, 2018

5

Functional mapping of the ligand binding sites of G-Protein coupled receptors

Tung M. Fong, Catherine D. Strader

Journal:

Medicinal Research Reviews

Year:

1994

Language:

english

File:

PDF, 888 KB

english, 1994

6

Nociception and inflammatory hyperalgesia in B2 bradykinin receptor knockout mice

Susan Boyce, Nadia M.J. Rupniak, Emma J. Carlson, Janine Webb, Joseph A. Borkowski, J. Fred Hess, Catherine D. Strader, Raymond G. Hill

Journal:

Immunopharmacology

Year:

1996

Language:

english

File:

PDF, 202 KB

english, 1996

7

1,2,3-Trisubstituted cyclohexyl substance P antagonists: significance of the ring nitrogen in piperidine-based NK-1 receptor antagonists

Sander G. Mills, Malcolm MacCoss, Dennis Underwood, Shrenik K. Shah, Paul E. Finke, Daniel J. Miller, Richard J. Budhu, Margaret A. Cascieri, Sharon Sadowski, Catherine D. Strader

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1995

Language:

english

File:

PDF, 283 KB

english, 1995

8

Structural model of antagonist and agonist binding to the angiotensin II, AT1 subtype, G protein coupled receptor

Dennis J. Underwood, Catherine D. Strader, Ralph Rivero, Arthur A. Patchett, William Greenlee, Kristine Prendergast

Journal:

Chemistry & Biology

Year:

1994

Language:

english

File:

PDF, 1.36 MB

english, 1994

9

Quinuclidine-based NK-1 antagonists I: 3-benzyloxy-1-azabicyclo[2.2.2]octanes

Eileen M. Seward, Christopher J. Swain, Kevin J. Merchant, Simon N. Owen, Verity Sabin, Margaret A. Cascieri, Sharon Sadowski, Catherine Strader, Raymond Baker

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 341 KB

english, 1993

10

Acyclic NK-1 antagonists: 2-benzhydryl-2-aminoethyl ethers

Brian J. Williams, Martin Teall, Jeffrey Mc Kenna, Timothy Harrison, Christopher J. Swain, Margaret A. Cascieri, Sharon Sadowski, Catherine Strader, Raymond Baker

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 431 KB

english, 1994

11

Potent, selective benzenesulfonamide agonists of the human β3 adrenergic receptor

Ann E. Weber, Robert J. Mathvink, Leroy Perkins, Jennifer E. Hutchins, Mari R. Candelore, Laurie Tota, Catherine D. Strader, Matthew J. Wyvratt, Michael H. Fisher

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 384 KB

english, 1998

12

Discovery of L-755,507: A subnanomolar human β3 adrenergic receptor agonist

Emma R. Parmee, Hyun O. Ok, Mari R. Candelore, Laurie Tota, Liping Deng, Catherine D. Strader, Matthew J. Wyvratt, Michael H. Fisher, Ann E. Weber

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 268 KB

english, 1998

13

Potent, selective human β3 adrenergic receptor agonists containing a substituted indoline-5-sulfonamide pharmacophore

Robert J Mathvink, Anna Maria Barritta, Mari R Candelore, Margaret A Cascieri, Liping Deng, Laurie Tota, Catherine D Strader, Matthew J Wyvratt, Michael H Fisher, Ann E Weber

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1999

Language:

english

File:

PDF, 339 KB

english, 1999

14

Molecular approaches to the discovery of new treatments for obesity

Catherine D Strader, D Euan MacIntyre, Mari R Candelore, Eric M Parker

Journal:

Current Opinion in Chemical Biology

Year:

1997

Language:

english

File:

PDF, 691 KB

english, 1997

15

Genetic analysis of the molecular basis for β-adrenergic receptor subtype specificity

Richard A. F. Dixon, Wendy S. Hill, Mari R. Candelore, Elaine Rands, Ronald E. Diehl, Mark S. Marshall, Irving S. Sigal, Catherine D. Strader

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1989

Language:

english

File:

PDF, 771 KB

english, 1989

16

1,4-Diacylpiperazine-2-(S)-[(N-aminoalkyl)carboxamides] as novel, potent substance P receptor antagonists.

Sander G. Mills, Mu Tsu Wu, Malcolm MacCoss, Richard J. Budhu, Conrad P. Dorn Jr., Margaret A. Cascieri, Sharon Sadowski, Catherine D. Strader, William J. Greenlee

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 354 KB

english, 1993

17

Ligand binding to the β-adrenergic receptor involves its rhodopsin-like core

Dixon, Richard A. F., Sigal, Irving S., Rands, Elaine, Register, R. Bruce, Candelore, Mari Rios, Blake, Allan D., Strader, Catherine D.

Journal:

Year:

1987

File:

PDF, 564 KB

1987

18

Amino–aromatic interaction between histidine 197 of the neurokinin-1 receptor and CP 96345

Ming Fong, Tung, Cascieri, Margaret A., Yu, Hong, Bansal, Alka, Swain, Christopher, Strader, Catherine D.

Journal:

Year:

1993

File:

PDF, 482 KB

1993

19

Molecular characterization of a common binding site for small molecules within the transmembrane domain of G-protein coupled receptors

Margaret A. Cascieri, Tung Ming Fong, Catherine D. Strader

Journal:

Journal of Pharmacological and Toxicological Methods

Year:

1995

Language:

english

File:

PDF, 764 KB

english, 1995

20

Novel molecular targets for the treatment of obesity

Catherine D Strader, Joyce J Hwa, Margaret Van Heek, Eric M Parker

Journal:

Drug Discovery Today

Year:

1998

Language:

english

File:

PDF, 187 KB

english, 1998

21

Effect of Chronic Central Administration of Glucagon-Like Peptide-1 (7–36) Amide on Food Consumption and Body Weight in Normal and Obese Rats

Jr. Harry R. Davis, Deborra E. Mullins, Jesse M. Pines, Lizbeth M. Hoos, Constance F. France, Douglas S. Compton, Michael P. Graziano, Edmund J. Sybertz, Catherine D. Strader, Margaret Van Heek

Journal:

Year:

1998

Language:

english

File:

PDF, 993 KB

english, 1998

22

Phosphorylation of the β-adrenergic receptor in intact cells: Relationship to heterologous and homologous mechanisms of adenylate cyclase desensitization

David R. Sibley, Kiefer Daniel, Catherine D. Strader, Robert J. Lefkowitz

Journal:

Archives of Biochemistry and Biophysics

Year:

1987

Language:

english

File:

PDF, 962 KB

english, 1987

23

cDNA Sequence and heterologous expression of the human neurokinin-3 receptor

Ruey-Ruey C. Huang, Anne H. Cheung, Kathryn E. Mazina, Catherine D. Strader, Tung Ming Fong

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 526 KB

english, 1992

24

Cloning and pharmacological characterization of a human bradykinin (BK-2) receptor

J. Fred Hess, Joseph A. Borkowski, Gretchen S. Young, Catherine D. Strader, Richard W. Ransom

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 751 KB

english, 1992

25

Cytoplasmic loop of β-adrenergic receptors: synaptic and intracellular localization and relation to catecholaminergic neurons in the nuclei of the solitary tracts

Chiye Aoki, Barbara A. Zemcik, Catherine D. Strader, Virginia M. Pickel

Journal:

Year:

1989

Language:

english

File:

PDF, 17.10 MB

english, 1989

26

Morphologic demonstration of clathrin-coated pits in frog and turkey erythrocytes

Mark C. Willingham, Catherine D. Strader, Robert J. Lefkowitz, Ira Pastan

Journal:

Experimental Cell Research

Year:

1984

Language:

english

File:

PDF, 1.25 MB

english, 1984

27

Specific activation of Gs by synthetic peptides corresponding to an intracellular loop of the β-adrenergic receptor

Anne H. Cheung, Ruey-Ruey C. Huang, Michael P. Graziano, Catherine D. Strader

Journal:

Year:

1991

Language:

english

File:

PDF, 307 KB

english, 1991

28

Synthetic segments of the mammalian βAR are preferentially recognized by cAMP-dependent protein kinase and protein kinase C

Allan D. Blake, Richard A. Mumford, H. Vincent Strout, Eve E. Slater, Catherine D. Strader

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 387 KB

english, 1987

29

Genomic organization and functional characterization of the mouse GalR1 galanin receptor

Suke Wang, Chaogang He, Maureen T Maguire, Anthony L Clemmons, Robert E Burrier, Mario F Guzzi, Catherine D Strader, Eric M Parker, Marvin L Bayne

Journal:

Year:

1997

Language:

english

File:

PDF, 1.08 MB

english, 1997

30

The GalR2 galanin receptor mediates galanin-induced jejunal contraction, but not feeding behavior, in the rat: differentiation of central and peripheral effects of receptor subtype activation

Suke Wang, Lorraine Ghibaudi, Tanaz Hashemi, Chaogang He, Catherine Strader, Marvin Bayne, Harry Davis, Joyce J Hwa

Journal:

Year:

1998

Language:

english

File:

PDF, 155 KB

english, 1998

31

Facilitation of acetylcholine release and improvement in cognition by a selective M2 muscarinic antagonist, SCH 72788

Jean E. Lachowicz, Ruth A. Duffy, Vilma Ruperto, Joseph Kozlowski, Guowei Zhou, John Clader, William Billard, Herbert Binch III, Gordon Crosby, Mary Cohen-Williams, Catherine D. Strader, Victoria Coff

Journal:

Year:

2001

Language:

english

File:

PDF, 210 KB

english, 2001

32

SCH 57790: A novel M2 receptor selective antagonist

Jean E. Lachowicz, Derek Lowe, Ruth A. Duffy, Vilma Ruperto, Lisa A. Taylor, Henry Guzik, Joan Brown, Joel G. Berger, Melissa Tice, Robert McQuade, Joseph Kozlowski, John Clader, Catherine D. Strader,

Journal:

Year:

1999

Language:

english

File:

PDF, 385 KB

english, 1999

33

Presenilin mutations in Alzheimer's disease: molecular models suggest a potential functional locus

Nicholas J. Murgolo, Joan E. Brown, Marvin L. Bayne, Catherine D. Strader

Journal:

Trends in Pharmacological Sciences

Year:

1996

Language:

english

File:

PDF, 1.28 MB

english, 1996

34

Amino terminal amino acid sequence of the major polypeptide subunit of Torpedo californica acetylcholine receptor

Michael W. Hunkapiller, Catherine D. Strader, Leroy Hood, Michael A. Raftery

Journal:

Biochemical and Biophysical Research Communications

Year:

1979

Language:

english

File:

PDF, 655 KB

english, 1979

35

The characterization of actin associated with postsynaptic membranes from Torpedo californica

Catherine Devine Strader, Elias Lazarides, Michael A. Raftery

Journal:

Biochemical and Biophysical Research Communications

Year:

1980

Language:

english

File:

PDF, 1.47 MB

english, 1980

36

Association of sequestered beta-adrenergic receptors with the plasma membrane: A novel mechanism for receptor down regulation

Catherine D. Strader, David R. Sibley, Robert J. Lefkowitz

Journal:

Year:

1984

Language:

english

File:

PDF, 684 KB

english, 1984

37

Biophysical and genetic analysis of the ligand-binding site of the β-adrenoceptor

Michael R. Tota, Marialuisa Rios Candelore, Richard A.F. Dixon, Catherine D. Strader

Journal:

Trends in Pharmacological Sciences

Year:

1991

Language:

english

File:

PDF, 429 KB

english, 1991

38

The extracellular domain of the neurokinin-1 receptor is required for high affinity binding of peptides

TungMing Fong, Hong Yu, Ruey-RueyC. Huang, CatherineD. Strader

Journal:

Regulatory Peptides

Year:

1992

Language:

english

File:

PDF, 34 KB

english, 1992

39

Mapping the ligand binding site of the NK-1 receptor

Tung Ming Fong, Ruey-Ruey C. Huang, Hong Yu, Catherine D. Strader

Journal:

Regulatory Peptides

Year:

1993

Language:

english

File:

PDF, 396 KB

english, 1993

40

(Thr-59)-insulin-like growth factor I stimulates 2-deoxyglucose transport in BC3H1 myocytes through the insulin-like growth factor receptor, not the insulin receptor

Margaret A. Cascieri, Gary G. Chicchi, Nancy S. Hayes, Catherine D. Strader

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1986

Language:

english

File:

PDF, 638 KB

english, 1986

41

Characterization of the binding and activity of a high affinity, pseudoirreversible morpholino tachykinin NK1 receptor antagonist

Margaret A Cascieri, Elzbieta Ber, Tung Ming Fong, Jeffrey J Hale, Frank Tang, Lin-Lin Shiao, Sander G Mills, Malcolm MacCoss, Sharon Sadowski, Michael R Tota, Catherine D Strader

Journal:

European Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 281 KB

english, 1997

42

Interaction of Substance P with the Second and Seventh Transmembrane Domains of the Neurokinin-1 Receptor

Huang, Ruey Ruey C., Yu, Hong, Strader, Catherine D., Fong, Tung Ming

Journal:

Year:

1994

Language:

english

File:

PDF, 807 KB

english, 1994

43

2( S )-((3,5-Bis(trifluoromethyl)benzyl)oxy)-3( S )-phenyl-4-((3-oxo-1,2,4-triazol- 5-yl)methyl)morpholine ( 1 ): A Potent, Orally Active, Morpholine-Based Human Neurokinin-1 Receptor Antagonist

Hale, Jeffrey J., Mills, Sander G., MacCoss, Malcolm, Shah, Shrenik K., Qi, Hongbo, Mathre, David J., Cascieri, Margaret A., Sadowski, Sharon, Strader, Catherine D., MacIntyre, D. Euan, Metzger, Josep

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 140 KB

english, 1996

44

Synthesis of Potent Cyclic Hexapeptide NK-1 Antagonists. Use of a Minilibrary in Transforming a Peptidal Somatostatin Receptor Ligand into an NK-1 Receptor Ligand via a Polyvalent Peptidomimetic

Hirschmann, Ralph, Yao, Wenqing, Cascieri, Margaret A., Strader, Catherine D., Maechler, Laurie, Cichy-Knight, Maria A., Hynes,, John, van Rijn, Rachel D., Sprengeler, Paul A., Smith, Amos B.

Journal:

Journal of Medicinal Chemistry

Year:

1996

Language:

english

File:

PDF, 300 KB

english, 1996

45

The carboxyl terminus of the hamster β-adrenergic receptor expressed in mouse L cells is not required for receptor sequestration

Strader, Catherine D., Sigal, Irving S., Blake, Allan D., Cheung, Anne H., Register, R.Bruce, Rands, Elaine, Zemcik, Barbara A., Candelore, Mari Rios, Dixon, Richard A.F.

Journal:

Year:

1987

Language:

english

File:

PDF, 2.45 MB

english, 1987

46

Identification of Residues Required for Ligand Binding to the β -adrenergic Receptor

Catherine D. Strader, Irving S. Sigal, R. Bruce Register, Mari Rios Candelore, Elaine Rands and Richard A. F. Dixon

Journal:

Proceedings of the National Academy of Sciences

Year:

1987

Language:

english

File:

PDF, 782 KB

english, 1987

47

[Part 2: Biological Sciences] || Topographic Studies of Torpedo Acetylcholine Receptor Subunits as a Transmembrane Complex

Catherine D. Strader and Michael A. Raftery

Journal:

Proceedings of the National Academy of Sciences

Year:

1980

Language:

english

File:

PDF, 1.27 MB

english, 1980

48

[Part 1: Biological Sciences] || Antibodies to the β -adrenergic Receptor: Attenuation of Catecholamine-Sensitive Adenylate Cyclase and Demonstration of Postsynaptic Receptor Localization in Brain

Catherine D. Strader, Virginia M. Pickel, Tong H. Joh, Mark W. Strohsacker, Robert G. L. Shorr, Robert J. Lefkowitz and Marc G. Caron

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 1.43 MB

english, 1983

49

[Part 1: Biological Sciences] || Reconstitution of β -adrenergic Receptors in Lipid Vesicles: Affinity Chromatography-Purified Receptors Confer Catecholamine Responsiveness on a Heterologous Adenylate Cyclase System

Richard A. Cerione, Berta Strulovici, Jeffrey L. Benovic, Catherine D. Strader, Marc G. Caron and Robert J. Lefkowitz

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 968 KB

english, 1983

50

Part 1 || Demonstration of the Transmembrane Nature of the Acetylcholine Receptor by Labeling with Anti-Receptor Antibodies

Catherine B. Devine Strader, Jean-Paul Revel and Michael A. Raftery

Journal:

The Journal of Cell Biology

Year:

1979

Language:

english

File:

PDF, 3.77 MB

english, 1979

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